Q1:
Describe the experimental design and hypothesis testing that you are currently planning and/or performing in your rotations or thesis lab, including:
What are sources of variation in the values you are measuring in your experiments, and what are some ways that you can account for this variation in your study design and statistical analyses?
When performing the experiments, are you using randomization or blinding and if not why?
Are your replicates biological (independent) or technical or both, and what is the independent sample size you are using?
Was the independent sample size of your experiments pre-determined using power calculations (if you don’t know ask someone in your lab, or even your PI) and if not, how was the sample size justified?
What is the hypothesis you are testing, and when evaluating your hypothesis do you think a one- or two-sided test is more appropriate and why?
(20 points)
Extra credit:
Read this PNAS paper on martial satisfaction from lecture: https://www.pnas.org/doi/10.1073/pnas.1222447110
Can you find any flaws in the study design that might confound the interpretation of whether online dating leads to greater marital satisfaction? Consider the concepts we learned in class in particular those that might apply to human subjects research
(1 point)