We are a biomedical research group in the Department of Pediatrics in the School of Medicine at the University of California, San Diego in La Jolla CA. We are also members of the UCSD Pediatric Diabetes Research Center, Bioinformatics and Systems Biology program, Biomedical Sciences program, Institute for Diabetes and Metabolic Health, and Institute for Genomic Medicine.

Our group studies the genetic basis and molecular mechanisms of complex disease, in particular type 1 and type 2 diabetes.

We use computational and molecular genetics to address contemporary questions about human genetic variation and its effect on genome function and disease risk. A primary interest is understanding relationships between disease-associated variation, transcription factor binding, chromatin accessibility and organization, and gene regulation.